OECD 439 - Žmogaus odos dirginimas, in vitro testas - Rekonstruota žmogaus epidermis, in vitro testavimo metodas
- OECD 439 / Skin Irritation Test (SIT) in a Reconstructed Human Epidermis (RhE) Model -
Skin Irritation in the regulatory hazard classification and labeling context is defined as the production of reversible damage to skin following a defined chemical exposure. The Skin Irritation Test (SIT) is an in vitro, non-animal test designed to identify those chemicals and mixtures capable of inducing moderate skin irritation (UN GHS Category 2 Skin Irritants1), and to discriminate UN GHS Category 2 Skin Irritants from UN GHS 3 Mild Skin Irritants as well as those not requiring classification for skin irritation potential.
INVITRO-CONNECT GmbH has extensive expertise with a wide variety of reconstructed skin-based protocols.
For more information please contact INVITRO-CONNECT GmbH for assistance in developing specialized protocols for your test materials.
INVITRO-CONNECT GmbH:
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